Endocrine Abstracts

The aim of the study was to assess the role of the estradiol and progesterone relationship during the late luteal phase and the occurrence of fibrocystic breast disease (FBD). The concentration of E2/P was measured in the group of women with FBD as study group and healty control group. All women had regular ovulation cycles. Blood samples for E2, P and prolactin determination were obtained in the morning at 8 am on days 21 and 24 of menstrual cycle. Significant mastalgia and m...

Introduction: The average age for physiological menopause is 50 years. Menopause before the age of 40 is usually defined as premature ovarian failure (POF). POF in adolescents is an extremely rare event and its occurrence raises important questions about the cause-and-effect relationship, which may signal genetic and systemic disorders.Design Case report: The 29-year-old first reported to an endocrinologist for secondary amenorrhea. The anamnesis reveale...

Introduction: There is a significant overlap of symptoms between polycystic ovary syndrome (PCOS) and thyroid disease, despite the fact that they are two different diseases. Both diseases individually affect a woman’s metabolic parameters and fertility, and their association makes them much more difficult to manage.Objective: To investigate the effect of elevated thyroid stimulating hormone (TSH) concentrations on metabolic and endocrine parameters ...

Introduction: The diagnostic criteria of polycystic ovary syndrome (PCOS) are still under discussion and the hormonal parameters, including anti-Mullerian hormone range and hyperandrogenism, are not determined. Serum AMH level has been proposed as a surrogate marker for PCOM and could, therefore, be integrated in the diagnostic classifications for PCOS\. The aim of the present study was to characterize hormonal features of PCOS and to establish the most important hormonal para...